Depressed, Guilty, or Shameful After Reading Through a Fashion Magazine for Only Three Minutes.

I stare stupidly at information technology. It'south nothing much to look at. Information technology'south only a small pile of habiliment: the shorts and tank meridian that I wear in bed, which I accept thrown on to the floor before getting into the shower. I stare stupidly at the dodder because I can't choice it up. It'southward amazing that I managed to shower, considering I know already that this is a bad twenty-four hours, one when I feel assaulted by my hormones, which I picture equally small-scale pilots in those huge Star Wars armoured beasts that turn me this way and that, implacable. On this morn, I wake up with fearfulness in my tum – fear of nothing – and I know information technology volition be a bad day.

For a while, I thought I could predict these days. I have had practice. This is my second menopause: the first was chemically induced seven years agone to treat my endometriosis, a condition that has riddled my insides with adhesions of endometrial tissue, and stuck my organs together. The adhesions are exacerbated by oestrogen; the drug switched it off. (The aforementioned drug can block other hormones and is as well used to treat paedophilia and prostate cancer.) I hated that menopause. It was a crash off a cliff into sudden insomnia and depression, and a complete eradication of sexual desire. "The symptoms will concluding six months," said the male ob-gyn, with a voice he idea was kind but that sounded simply casual. They lasted far longer. The nurse giving me the first injection said, "He keeps prescribing this stuff, but women hate it."

This menopause is the natural i. I'k ii years in. It doesn't feel natural. It feels similar a derangement. With each menopause, I accept called to accept hormone replacement therapy (HRT). The first time because I wanted my sleep back. This fourth dimension because I spent a year researching menopause for a magazine article, and because I accept weighed the risks and judged them adequate, and considering I know what happened terminal time, when I was broken. The 2 occasions when I asked for HRT are the only two on which I have cried in a dr.'s office.

Every Wednesday and Sabbatum, I take two 100mg transdermal patches of estradiol (a form of oestrogen). I fix them to my abdomen, swapping sides each time. They never fall off, though I go running for hours at a fourth dimension and sweat. This is the maximum dose of oestrogen, and it took about a year for me to sympathize that I needed this amount – a twelvemonth of peeling pare, sore tendons, poor sleep, awful sadness, inexplicable weeping and various other "symptoms" of menopause that you tin can find listed if you await beyond the hot flushes and insomnia. Oestrogen is more powerful and more wide-ranging than is assumed, and its removal or diminishment brings effects ludicrously understated by "the modify".

A friend gave me admission to her university library and I starting time to swim among papers, sometimes floundering. I larn that oestrogen is a gonadal steroid produced by the ovaries, and essential to female reproduction. It is a sex hormone but – it is now known – far more as well. There are receptors for oestrogen all over the body. In the brain, the densest amounts are in the amygdala, the hippocampus and the hypothalamus. Oestrogen influences serotonin, dopamine, glutamate and noradrenaline. It is involved in cognitive function. Its diminishment can impair verbal dexterity, memory and clarity of idea. Recently, scientists discovered that oestrogen is likewise produced in the adrenal glands, breasts, adipose tissue and brain. This is astonishing. But so is the extent of the unknown.

Perimenopausal women (whose periods may be irregular, who accept symptoms, but who are not yet postmenopausal) are twice as likely to take depressive symptoms or low than premenopausal women. Perimenopausal women who were vulnerable to depression during the menstrual bicycle are more susceptible to depression when they enter menopause or its hinterlands. This is accepted, only in that location is disagreement about how to fix it. Antidepressants frequently don't piece of work. Studies show both success and failure when women are given oestrogen to counter low. Controversy exists over whether the menopausal transition is a risk factor for the development of depression, I read. And, I call up, the person who wrote that has probably never been on a menopause forum, where women's stories and pain would make me weep, if I didn't experience like weeping already, from menopause.

Because I accept a womb – though information technology is likely of no use for fertility, cheers to the endometriosis – I as well have progesterone for 10 days a month. This induces the womb to shed its endometrium, which may otherwise thicken to cancer-risky proportions. Then I still drain, and choose to. I knew from my inquiry that the gentlest version of progesterone is micronised, something that my doc had to look upwards. I didn't know that taking information technology orally, every bit I had for many months, would bring me profound sadness, fatigue, weight gain, awfulness. That wasn't something I discovered in my research, and no one told me.


I can't choice up the wearing apparel. I can't explain the granite of that "can't", the fashion information technology feels impossible to beat. Await at me looking at the pile and y'all volition think: Just pick information technology up. For fuck'southward sake. But I don't. I look at it, and the thought of accomplishing annihilation makes my fearfulness and despair abound. Every idea brings on another, and that prospect is frightening. I feel stupid and maudlin and dramatic. A privileged freelance author who does not have a full-fourth dimension job that requires her presence in an part and tin be indulgent of what the medical profession calls "low moods". In fact, plenty of menopausal women exit their jobs, endure wrecked relationships, suffer and cope. Or don't.

The phrase "depression moods" is belittling. My low is non simply feeling miserable or glum. I know what that feels like. I know that that can be fixed by fresh air or effort. This low is dysfunction, derangement.

I feel terrified. I have no reason to feel fright. But my torso acts as though I do: the blood rushing from my gut to my limbs in case I need to abscond, leaving the fluttering emptiness that is called "butterflies", though that is too pretty a description.

Still, I gear up off on my bicycle to my writing studio. I hope I can overcome the twenty-four hours. I always hope, and I am ever incorrect. A few hours afterwards, I find myself cowering in my workspace, a studio I rent in a complex of artists' studios, scared to go downstairs to the kitchen considering I tin can't bear to talk to anyone. I have done nothing of employ all day. Every now and and so, I terminate doing nothing and put my head in my easily because information technology feels rubber and comfortable, like a refuge. I look underneath my desk-bound and retrieve I might sit down in that location. There is no logic to this, except that information technology is out of sight of the door and no one will discover me.

Still, when the phone rings, I answer it. It'southward my female parent calling. I am hopeful that I can manage information technology and mask the panic. I haven't spoken to my mother for a few days, and would like to. It goes well for a few minutes, because I'm non doing the talking. Then she asks me whether I want to accompany her to a posh dinner, several weeks hence. She doesn't sympathize when I ask to exist given some time to think about it. "Why can't you lot decide now?" I say it's ane of the bad days, but I know this is a mixed message: if it's that bad, how am I talking on the phone and sounding all right? Because I am a duck: talking serenely above, churning below, the weight on my chest, the grab in my throat, the inexplicable distress. I endeavour to explain just I'm as well trying difficult not to weep, and so I explain it badly.

Hormone replacement therapy tablets
Hormone replacement therapy tablets. Photograph: Alamy

She doesn't empathize. This is not her fault. She is a empathetic woman, but she had an easy menopause, then piece of cake that she can say, "Oh, I barely remember information technology." She doesn't understand depression, though both her children experience it, because she has never had it. "But you sounded well," she says, "I idea you were all right." Now she says: "I don't understand how your not beingness well is stopping you lot deciding whether y'all want to get to dinner." Because it is a conclusion, and a decision is too hard, requiring many things to happen in my brain, and my brain is as well busy being filled with fear and panic and black numbness. There is no room to spare.

I hang up. I stay there for a while, sitting on my burrow, wondering how to face opening the door or leaving my studio or cycling abode. All these actions seem equally incommunicable.

On days like this, there are only 2 places to be. One is in my darkened bedroom with my cat lying side by side to me. On days similar this she takes intendance to prevarication closer to me than usual, because she knows. Maybe my darkness has a smell.

The other place to be is in unconsciousness.

These are the rubber places because everything is serenity. It is on the bad days that I realise what a cacophony of impressions we walk through every twenty-four hour period, and how good we are at receiving and deflecting, equally required. Every day, we filter and sieve; on the bad days, my filters fail.

I sometimes call these bridge days, afterwards a footbridge near my studio that goes at a great peak over the busy A64 road. On days like this, that span is a danger for me. I am non suicidal, but I have ever had the urge to jump. This is a thing with a proper name. HPP: high identify phenomenon. The French call it l'appel du vide. So very Sartre: the call of emptiness. The A64 is the opposite of emptiness, but still, it is a danger. Today I don't take the filter that we must all have to function: the one that stops the states stepping into traffic or fearing the cars or buses that can kill usa at whatsoever time.

I avoid the bridge. I cycle home, trying not to rage at drivers who cutting me off and ignore me. I have no room for rage along with everything else. Thoughts that would normally flow now snag. Every observation immediately triggers a negative thread, a spiral and a worsening. On a cheerio, I can pass a child and a mother and recollect: how nice. Nothing more. Fleeting. Unimportant. On a bad twenty-four hours, I see the same and think of my own infertility, how I have surely disappointed my mother by non giving her grandchildren; how it is all besides belatedly, and what accept I done with my life, and my book will be a failure and today is lost and I can't afford to lose the time. It goes on and on. Snagging thoughts that drag me down, that are relentless.

When I get inside my firm, I cry. I try to picket something or read, simply null interests me. This is some other symptom of low, called anhedonia: forgetting how to take pleasure. The best thing to do is sleep away the day, as much equally I can.

Toward evening, I begin to feel a faint foolishness. This is my sign: embarrassment. Shame at the twenty-four hours and at my management of it. When I am able to feel that and see that, I am getting better. Now I manage to watch TV, though only strange-linguistic communication dramas. Foreign words go somewhere shallower in the brain; they are less heavy. Only shortly I switch it off. I don't intendance about the plot. I don't care almost anything. I accept a sleeping pill to get the day over with, and so the better next day tin can begin.

Xx-four hours before, I had been wearing a Santa hat, running for five miles through icy bogs on a Yorkshire moor, happy to exist doing that for fun, happy to be alive.


A pril 4. Slumber mostly OK; a few days of melatonin after stopping progesterone. Last night I was exhausted, only slept badly. Mood difficult but not dreadful. Angry and irritated. No drain after progesterone. Peeling skin. Weepy and panic at present. Can I face people?

Depression, wrote William Styron, is a substantive "with a bland tonality and lacking any magisterial presence, used indifferently to describe an economic pass up or a heat in the ground, a truthful wimp of a word for such a major disease". It was pioneered by a Swiss psychiatrist who, Styron thought, perchance had a "tin ear" and "therefore was unaware of the semantic impairment he had inflicted by offering 'depression' equally a descriptive noun for such a dreadful and raging disease".

"Blackness dog." "Walking through treacle." "Low moods." Nothing I accept read of depression has conveyed the crippling weight of it.

I exercise not have depression co-ordinate to most authoritative clinical definitions of the condition. Depression is a long-term chronic illness. Mine is unpredictable, and before I got my HRT dose right, information technology lasted weeks at a time; merely usually, these days, it lasts no more than 24 hours. My now-and-thens do not authorize as a disease. I practise not count as depressed. Instead, I am i of the women of menopause, who struggle to sympathize why we feel such despair, why now we cry when earlier we didn't, why understanding what is left and what is right takes a fraction longer than it used to: all this is "depression mood" or "brain fog". These diminishing phrases convey nothing of the strength of the anguish or grief that attack united states.

I take never been sunny. People who can ascension from their beds and come across joy without working at it, they have always been a mystery. I still experience guilty for in one case request a cheery person, early in the forenoon, why he was so happy – I fabricated it sound like an accusation. Cheeriness ever seems like an enviable gift. I have e'er been susceptible to premenstrual upheaval: two days a month when things feel awful, as though they accept never been anything else. I endured them. Now and so, in that location have been therapists and antidepressants, and, for the final few years, running in wild places, which is the best therapy. I accept managed.

Then I became a menopausal woman. In the eyes of evolution, that makes me a pointless person. I can no longer reproduce, if I e'er could. The grandmother theory of menopause – that women live beyond their reproductive utility in order to treat grandchildren – doesn't persuade me. Also, I have no grandchildren. I cannot account for how awful menopause tin can be, unless I think that we were not meant to survive it.


T hursday fourteen. Removed old patch, added one-half a new one. Mood immediately plunged. Awful: anhedonia, feet, panic, weepiness. I nonetheless ran, but stopped to weep in the eye. So ill of this, and I can't work.

For months, I resisted HRT. I endured equally my periods got erratic, every bit I lost my ability to sleep through the night, as my temperature rose furiously at unpredictable moments.

I woke up in the night boiling hot and pouring sweat. I apply "pouring" deliberately because I was drenched. Sometimes, I woke upward freezing because I was covered in cold sweat. Every athlete knows to modify clothes as shortly equally possible because sweat chills and then fast. Every dark, it was as though I was running several races. I woke up drawn, stinking and angry that something so common, something that affects millions of women, is even so such a medical mystery. Why do we get hot flushes? We don't know. Why is sleep broken? We don't know. Why are we the only creatures to become menopause apart from two types of whales? Nosotros don't know.

My physician prescribed a low dose of HRT and a visit to a specialised menopause dispensary, of which there are far too few. My menopause medico prescribed a higher dose of HRT, but the symptoms continued, and were far more numerous than the hot flushes and insomnia to which menopause is usually reduced in common perception. I made a listing: at various points, my pare peeled, my ears rang with tinnitus, my posterior tibial tendon swelled, my lubrication disappeared, my eyes dried and then it felt as if I had grit in them, my jaw locked. The menopause doctor prescribed a nevertheless higher dose, and yet they came. Finally, I sat in her office and said I couldn't call up straight.

X-ray of an electrical fan
Photograph: Nick Veasey/Getty

I felt like I was going mad. I became clumsier. I forgot everything: names, events, appointments. My partner began to say, advisedly, too often, "Aye, you've mentioned that," in the same manner I used to say it to my dad when he had dementia. The menopause physician said, "This is simply your age." The year earlier, aged 46, I had had no brain defoliation. Forty-seven, and menopausal, I did. And she was a specialist. I never went back.

I paid to see a private menopause specialist who immediately said I could be on the maximum dose of oestrogen, that she couldn't sympathise why no 1 had told me that taking progesterone orally causes many women troubles such as profound fatigue and low, or that I could take it as a pessary in half the dose for less of the fourth dimension, which would exist meliorate (it is). She also prescribed testosterone, a clinical determination that is controversial in the small circle of medical professionals who take an interest in menopause. It is unnecessary, say sceptics, because the ovaries produce enough testosterone – and mine are withal at that place, though sputtering into dysfunction. Only it can help, say others, considering testosterone tin can lift energy and mood. Perhaps I would get a libido dorsum. Perhaps I would remember what want feels like, rather than looking at my partner and thinking how lovely he is, merely distantly, through a glass pane, as if that idea had nothing to do with me.

I took my new boxes of patches, a pump gel of oestrogen to top upward with on the bad days, my precious testosterone, and went dwelling with hope. It took months, only things stabilised. Now, there is never more than than one bad twenty-four hours at a time. On the good days, I am at peace with my age, with what I accept washed, with who I am, menopausal or not. I delight in what I tin practise, and when I run, I hurtle headlong down a steep descent with the joy of a child, aged nearly fifty. Merely on other days, that woman seems like someone else.


One thousand onday 25. Starting time morning I oasis't felt dread and weepiness. Not giddy like before, but like things are possible. Simply as well scared of mood flipping – and it did. Horribly. Weepy, panicking, total anhedonia. I oasis't left the house. At 3 .30 I went to bed and woke upwardly at half-dozen. I feel greatly sorry, black, AWFUL. Did it all change after I drank java? Tuesday 26. No java. Panic, dread, weepy. Can't focus, can't wash up.

I grasp for reasons. I look for patterns. I keep a diary for 18 months. If I tin understand the patterns, I can predict the bad days and allow for them. I tin can plan for them. Tom Cruise in Minority Report had "pre-crime" to prevent and disrupt future criminal threats. Perhaps I tin have pre-depression. For many months, I recall that the bad days come when my oestrogen dips on the last day before I get new patches. I stop scheduling things on Mondays and Fridays. But then the pattern changes, and so I know it never was a pattern. Sometimes it'south a Tuesday. Sometimes, a Sunday. I can't tell. I give up the diary.

I attempt to take command by beingness less embarrassed. One time, when I still had flushes and was out at dinner, I got out my fan and a relative said: "Must you?" I don't understand this reaction. People are not mortified by cancer patients on chemo who sweat and use fans. Is it because menopause is to do with periods? Is it because women's wellness must be subconscious and placidity? Is it considering women do hide it? I tin't think why the irregularities of the hypothalamus should be socially unacceptable. I kept using my fan for as long every bit I needed to, though I felt faintly uneasy.

The simply acceptable identify for menopause is in menopause jokes. The humour that masks distress and shame. The adult female in a meeting who laughs off her sweating, who talks of "ability surges". The comedians and their mothers-in-law and their hot flushes. What if it came out of jokes and into accepted conversation?

For many months, I told people I was "unwell". Not crippled, non weeping, not disabled. "Unwell." The implication: that at that place is something physically wrong, a proper illness. What if I told everyone I had a severe headache? They would understand. Then, one day, as I sit at my computer and call back of my writing borderline and feel despair, I try to read medical literature and instead put my head in my hands. I decide to write to the commissioning editor, even though nosotros take not worked together earlier and this may class her stance of me, and say: I can't function today. I can't write. And it is considering of depression. Delight give me leeway. Information technology shames me to write it, but I exercise. And I practise it once again, when needed. And then far, every response has been profoundly kind. I should take washed it sooner.

Mental illness. Such an odd concept. How strange to put a division between mental and concrete illness, as if the brain is not in the body. Every bit if emotions are not regulated by the brain. As if feelings are not linked to hormones. And yet mental illness is put in a different category. Easier to fix, to underfund, to sweep into the dark corner of the unspoken. Imagine the contrary. Broken your ankle? Cheer up. Third-degree burns? Chin up. Think yourself improve, you with your chronic lymphocytic leukaemia. Grin.


Thou ay 4. Finally felt better yesterday . Tweeted fury about BBC menopause dr. and all its talk of "low moods". Messaged with a doctor who thinks 50mg of estradiol is likewise low and particularly for someone who was prone to PMT. She also thought I should try testosterone. Went downstairs and put another patch on. Retroactively furious with doc for sticking so firmly to dose, but perhaps I played down the depression. Today I slept well. Mood skillful. A feeling in my stomach that is positivity, similar I tin can do things.

I wake gloomy, my head foggy apparently from just one glass of prosecco the evening earlier. The room is hot, the city noises are infuriating. I put new oestrogen patches on my belly. I smear testosterone gel, two pea-sized globs, on my inner thighs. I go through the motions of other activities and look. One-half an hour later, as I am walking to the station, I feel a quiet inundation of practiced mood. It feels as though the oestrogen is lifting me slightly. I picture a tide floating buoys college and higher in a harbour. Oestrogen is hefting and hauling me out of depression, for today.

This is my theory. It is unproven, co-ordinate to the literature. I wish the urge to meliorate understand the extent of oestrogen's reach, and the devastation its fluctuation can bring, had happened decades ago. There has been more research in recent years, only I doubt that the driver for this knowledge is how poorly menopause is treated or understood; information technology's probably that oestrogen is implicated in college rates of Alzheimer's disease in postmenopausal women. There is coin in Alzheimer's, simply not in making women'due south lives amend.


Friday 22. Woke up at 10. Awful, awful, awful. Got upward at 12 and ran x miles, got back and burst into tears. Profound sadness, depression, weepiness. One of the worst withal. Panic at night.

My mother says, the solar day after another bad day: "I feel and so awful for you. Why can't they set up it?" They are doing all they tin, I say. I don't really believe this. The trouble with women is nosotros cope. We always practise.

I keep fit. I gave upwards alcohol for months, reasoning that it plunges me into depression the next day – and I tin produce those days all on my ain without paying coin to make them happen. Over the years, I take taken citalopram, sertraline, black cohosh, scarlet clover, omega iii, magnesium, iron, vitamin D. For a while, I saw a serene herbalist, who mixed dark potions and told me I should eat chickpeas and tofu to get their phytoestrogens to demark to the receptors all over my body. Many perimenopausal women with low are prescribed antidepressants. I hope theirs work, as mine did zippo. I know the iron helps, and I think the magnesium does, too, considering when I forget to take information technology, I start to feel stupider.

In scientific papers, researchers argue about whether women feeling depressed in menopause (pre-, peri-, post-) are actually just experiencing the ups and downs of life. We are brought low, they reason, by the hot flushes and sleeplessness, not past hormonal fluctuations. Or we are diminished past life. At that age, I read, women may accept ageing parents to care for; grown children and an empty house; empty marriages. Their depressive symptoms are a mourning for who they were and what is to come. They have what is chosen "the redundancy syndrome". It'south but coincidence that they are too menopausal. "Research has institute," I read, "that depressed mood and depressive disorder in middle-aged women are related less to menopause than to the vicissitudes of life."

I bristle at this. Although I wonder. I remember a month in France when I had not a single bad day. I detect that my mood lifts once my volume is written and its huge pressure level is likewise lifted. I wonder: is my problem not menopause-specific low, but that the removal of oestrogen leaves me less protected against my natural lows? This theory lasts until the next bad day, when I remember how elemental it feels.


May ii. I slept fine and took no pills, but today was the same. Sad, weepy, furious. I can collaborate with people, but in-between is awful. I went home at 3 and went to bed until 6. I hate this.

Today. Today is a decent day. It has taken me months to write this essay, because when I am bad, I can't write, and when I am not, I don't want to remember. Tomorrow? My menopausal status is beingness masked past HRT, so I won't know when I become postmenopausal until I dare to stop my artificial bolster of hormones. My postmenopausal friends tell me everything is improve on the other side. I want to believe them, and inquire my doctor, a young woman half my age, when I can finish taking HRT and what will happen if I do. She says: "Four years? That'due south about right." Stay on HRT for iv years, wean yourself off information technology, and and so see. This ways that in lodge to get off HRT I accept to plan for a fourth dimension in my life when I can take chances being brutalised by depression and insomnia for weeks at a stretch, when I might crash to the lesser over again. Even on a good mean solar day, I think that time will exist never.

This is an edited version of a piece that offset appeared on the New York Review of Books Daily

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